Nortriptyline

Nortriptyline – Treatment for Depression, Nerve Pain, and Sleep Problems

What is Nortriptyline?
Nortriptyline is a prescription antidepressant that belongs to a group of medicines called tricyclic antidepressants (TCAs). It’s primarily used to treat depression, but it is also effective for managing nerve pain (neuropathic pain), migraine prevention, and sleep disturbances when prescribed in lower doses.

It helps improve mood, relieve chronic pain, and support better sleep quality.

How Does Nortriptyline Work?
Nortriptyline works by increasing the levels of serotonin and norepinephrine in the brain — two important neurotransmitters that help regulate mood and pain perception.
By restoring this chemical balance, Nortriptyline helps reduce depressive symptoms, ease nerve pain, and improve overall emotional well-being.

Who Should Not Use Nortriptyline?
Do not take Nortriptyline if you:

• Are allergic to nortriptyline or other tricyclic antidepressants.

• Are taking or have recently taken monoamine oxidase inhibitors (MAOIs).

• Have severe liver disease, heart problems, or a recent heart attack.

Consult your doctor before taking Nortriptyline if you have glaucoma, epilepsy, diabetes, bipolar disorder, or a history of urinary retention or constipation.

Possible Side Effects
Like all medications, Nortriptyline may cause side effects. Common ones include:

• Drowsiness or dizziness

• Dry mouth

• Constipation

• Blurred vision

• Weight gain or appetite changes

• Sweating

More serious side effects, though rare, can include irregular heartbeat, confusion, mood changes, or allergic reactions. Seek medical help immediately if these occur.

Precautions and Interactions
Before using Nortriptyline, tell your healthcare provider if you:

• Are pregnant, planning pregnancy, or breastfeeding

• Are taking other antidepressants, sedatives, or painkillers

• Consume alcohol, which can increase drowsiness and dizziness

Avoid driving or operating heavy machinery until you know how Nortriptyline affects you.
Do not stop taking it abruptly — your doctor will help you taper the dose gradually to prevent withdrawal effects.

Storage Instructions
Store in a cool, dry place below 25°C, away from direct sunlight and moisture.
Keep out of reach of children.

Summary
Nortriptyline is a tricyclic antidepressant used to treat depression, nerve pain, and sleep problems. By balancing brain chemicals that affect mood and pain, it helps relieve symptoms and improve quality of life when taken as prescribed under medical supervision.